Bis-aryloxy(amino)-triazinyl-oxy(amino)aryl derivatives, their preparation and their use as antiviral agents

This invention provides triazine ring containing compounds useful as pharmaceuticals, especially for treating viral infections, particularly infections by respiratory syncitial virus and pharmaceutical compositions containing these compounds. The compounds have the general structure: wherein: A is a moiety selected from the group consisting of C' is selected from -SO3H, -OSO3H, -OH, or -COOH; B' is -NH, -NR or O; R is selected from H, (C1-C6) lower alkyl, straight or branched, wherein the carbon atoms may be optionally substituted with C1, Br, F, OH or CN; X is C1, F, or the moiety U' is selected from the group of -SO2, -CO, -NC(O), or -NC(S); W' is selected from the moieties: Y is -(CH2)n-; n is 0 to 6; m is 0 to 2; Z is selected from H, CH3, CF3, -CH2-(halogen), where halogen is C1, Br, F or I, -CH2OH, -COOH, -COO(C1-C6) lower alkyl straight or branched, -CONR R , CN or and R , in each occurrence, is independently selected from H or (C1-C6) lower alkyl; and the pharmaceutically acceptable salts and esters thereof.