Nucleic acid constructs for the cell cycle regulated expression of genes, cells comprising said constructs and their use for the preparation of medical compositions

Nucleic acid constructs for the cell cycle regulated expression of genes, cells comprising said constructs and their use for the preparation of medical compositions

A new nucleic acid construct for cell-cycle regulated expression of at least one gene (I) comprises: (a) an activating sequence; (b) a promoter module including nucleotide sequences that separately bind members of the E2F and CHF protein families; and (c) (I), encoding an active agent. Also new are...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SEDLACEK, HANS-HARALD, DR, MUELLER, ROLF, DR, ZWICKER, JOERK
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:A new nucleic acid construct for cell-cycle regulated expression of at least one gene (I) comprises: (a) an activating sequence; (b) a promoter module including nucleotide sequences that separately bind members of the E2F and CHF protein families; and (c) (I), encoding an active agent. Also new are isolated cells containing the constructs.