Molecular cloning and expression of human IL-3

A cDNA encoding human interleukin-3, also designated herein hIL-3 or hmulti-CSF, has been disposed in expression systems and caused to produce hIL-3 substantially free of impurities normally accompanying this protein as it is produced inter allia by peripheral blood lymfocytes in nature. The resulti...

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Hauptverfasser: VAN LEEN, ROBERT WILLEM, WAGEMAKER, GERARD, DORSSERS, LAMBERTUS CHRISTIAAN JOHANNES, VOS, YVONNE JOHANNA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A cDNA encoding human interleukin-3, also designated herein hIL-3 or hmulti-CSF, has been disposed in expression systems and caused to produce hIL-3 substantially free of impurities normally accompanying this protein as it is produced inter allia by peripheral blood lymfocytes in nature. The resulting hIL-3 can be produced in practical amounts and is useful in a variety of therapeutic and diagnostic protocols.