CONTROLLED RELEASE DEVICE

PCT No. PCT/GB93/02271 Sec. 371 Date Jun. 27, 1995 Sec. 102(e) Date Jun. 27, 1995 PCT Filed Nov. 4, 1993 PCT Pub. No. WO94/09746 PCT Pub. Date May 11, 1994A controlled release capsule comprises a male plug (2) formed of a water-swellable hydrogel which is engaged with a neck portion (4) of a female...

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Bibliographische Detailangaben
Hauptverfasser:	RASHID, ABDUL, BINNS, JULIE, STEPHANIE, MACKIE, JAMES, LEONARD, STEVENS, HOWARD, NORMAN, ERNEST
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BABY COMFORTERS CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY DEVICES FOR RECEIVING SPITTLE DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:	PCT No. PCT/GB93/02271 Sec. 371 Date Jun. 27, 1995 Sec. 102(e) Date Jun. 27, 1995 PCT Filed Nov. 4, 1993 PCT Pub. No. WO94/09746 PCT Pub. Date May 11, 1994A controlled release capsule comprises a male plug (2) formed of a water-swellable hydrogel which is engaged with a neck portion (4) of a female body (6). The capsule is intended to deliver two dosages of pharmaceutically active material at different times. A water soluble cap (8) is fitted over mouth (14) of the body, and defines a first volume (9) containing a first unit dosage (10). A second unit dosage (12) is contained within a second volume (11) defined by the plug and the female body. When the capsule is swallowed by a patient, the cap dissolves quickly in the aqueous medium within the gastro-intestinal tract and releases the first dosage. The aqueous medium then comes into contact with the hydrogel plug which swells and becomes disengaged from the body, usually in the intestine, thereby releasing the second dosage a predetermined time after the first dosage.