NOVEL CARBAPENEM DERIVATIVES
Novel carbapenem derivatives, represented by the following formula (I), having a substituted or unsubstituted imidazoÄ5,1-bÜthiazolium-6-ylmethyl group at the 2-position are disclosed. The compounds represented by the formula (I) have potent antibacterial activity against a wide spectrum of bacteria...
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creator | ISHII, MIYUKI AIHARA, KAZUHIRO TOYOOKA, YUMIKO ATSUMI, KUNIO SETSU, FUMIHITO KANO, YUKO SASAKI, TOSHIRO IWAMATSU, KATSUYOSHI SHIOKAWA, SOHJIRO TAMURA, ATSUSHI |
description | Novel carbapenem derivatives, represented by the following formula (I), having a substituted or unsubstituted imidazoÄ5,1-bÜthiazolium-6-ylmethyl group at the 2-position are disclosed. The compounds represented by the formula (I) have potent antibacterial activity against a wide spectrum of bacteria from Gram-positive bacteria to Gram-negative bacteria including Pseudomonas aeruginosa and, in addition, have potent antibacterial activity against various beta -lactamase-producing bacteria and MRSA and are very stable against DHP-1. |
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The compounds represented by the formula (I) have potent antibacterial activity against a wide spectrum of bacteria from Gram-positive bacteria to Gram-negative bacteria including Pseudomonas aeruginosa and, in addition, have potent antibacterial activity against various beta -lactamase-producing bacteria and MRSA and are very stable against DHP-1.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
title | NOVEL CARBAPENEM DERIVATIVES |
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