NOVEL CARBAPENEM DERIVATIVES

NOVEL CARBAPENEM DERIVATIVES

Novel carbapenem derivatives, represented by the following formula (I), having a substituted or unsubstituted imidazoÄ5,1-bÜthiazolium-6-ylmethyl group at the 2-position are disclosed. The compounds represented by the formula (I) have potent antibacterial activity against a wide spectrum of bacteria...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ISHII, MIYUKI, AIHARA, KAZUHIRO, TOYOOKA, YUMIKO, ATSUMI, KUNIO, SETSU, FUMIHITO, KANO, YUKO, SASAKI, TOSHIRO, IWAMATSU, KATSUYOSHI, SHIOKAWA, SOHJIRO, TAMURA, ATSUSHI
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Novel carbapenem derivatives, represented by the following formula (I), having a substituted or unsubstituted imidazoÄ5,1-bÜthiazolium-6-ylmethyl group at the 2-position are disclosed. The compounds represented by the formula (I) have potent antibacterial activity against a wide spectrum of bacteria from Gram-positive bacteria to Gram-negative bacteria including Pseudomonas aeruginosa and, in addition, have potent antibacterial activity against various beta -lactamase-producing bacteria and MRSA and are very stable against DHP-1.