2-(Indan-1-one-2-yl-alkyl)-1-phenylalkyl-piperidines and processes for their preparation

2-(Indan-1-one-2-yl-alkyl)-1-phenylalkyl-piperidines and processes for their preparation

Processes are provided for preparing cyclic amine compounds defined within the formula: in which J is indanyl, indanonyl, indenyl, indenonyl, indanedionyl, tetralonyl, benzosuberonyl, indanolyl or a divalent group thereof, K is phenyl, an arylalkyl or cynnamyl, B is -(CHR22)r-, R22 being H or methyl...

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Hauptverfasser: KARIBE, NORIO, OGURA, HIROO, HIGURASHI, KUNIZOU, ARAKI, SHIN, TSUCHIYA, YUTAKA, SUGIMOTO, HACHIRO, KOSASA, TAKASHI, SASAKI, ATSUSHI, IIMURA, YOUICHI, YAMATSU, KIYOMI, KOSOSA, MICHIKO, KUSOTA, ATSUHIKO, YAMANISHI, YOSHIHARU
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Processes are provided for preparing cyclic amine compounds defined within the formula: in which J is indanyl, indanonyl, indenyl, indenonyl, indanedionyl, tetralonyl, benzosuberonyl, indanolyl or a divalent group thereof, K is phenyl, an arylalkyl or cynnamyl, B is -(CHR22)r-, R22 being H or methyl, -CO-(CHR22)r-, =(CH-CH=CH)b-, =CH-(CH2)c- or =(CH-CH)d= and the ring including T and Q is piperidine. The compound is useful for the preparation of pharmaceutical compositions and for medicaments effective against senile dementia.