MINIATURIZED FLOW THERMOCYCLER

In thermally controlled biochemical or molecular biological processes, partic. for polymerase chain reactions in which DNA sequences are multiplied, a miniaturised flow thermocyclic appts. is formed by a Si or glass chip which contains a sample receiving area (1) for liq. media and ≥ 1 heating zone...

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Bibliographische Detailangaben
Hauptverfasser:	DILLNER, ULRICH, BODNER, ULRICH, KOEHLER, JOHANN, MICHAEL, POSER, SIEGFRIED, BAIER, VOLKER, SCHIMKAT, DIETER
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	In thermally controlled biochemical or molecular biological processes, partic. for polymerase chain reactions in which DNA sequences are multiplied, a miniaturised flow thermocyclic appts. is formed by a Si or glass chip which contains a sample receiving area (1) for liq. media and ≥ 1 heating zone (2) and one cooling zone (3). The sample receiving area comprises a meander-shaped arrangement in a single plane, formed by etching trenches in the plate and covered by a chip (10) contg. grooves (12) providing thermal insulation between heating and cooling zone areas.