3-Benzyl-benzothiophenes

This invention relates to the fields of pharmaceutical and organic chemistry and provides novel 3-benzyl-benzothiophenes which are alpha -substituted with ether, thioether amino, hydrazino, cyano or halo that are useful for the treatment of the various medical indications associated with post-menopa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: MUEHL, BRIAN STEPHEN
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:This invention relates to the fields of pharmaceutical and organic chemistry and provides novel 3-benzyl-benzothiophenes which are alpha -substituted with ether, thioether amino, hydrazino, cyano or halo that are useful for the treatment of the various medical indications associated with post-menopausal syndrome, as well as estrogen dependent diseases including cancer of the breast, uterus and cervix. The present invention further relates to intermediate compounds and processes useful for preparing the pharmaceutically active compounds of the present invention, and pharmaceutical compositions.