Process for the preparation of racemic aminoalcohols

Process for the preparation of racemic aminoalcohols

Prepn. of racemic aminoalcohols of formula (I) by redn. of alpha -oximiocarboxylic acids or their esters of formula (II) is carried out using an alkali metal borohydride, in combination with hydrogen chloride or sulphuric acid as activator, in a solvent. R1 = linear, branched or cyclic alkyl, aralky...

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Bibliographische Detailangaben
Hauptverfasser: JAHN, WILFRIED, DRAUZ, KARLHEINZ, DR, SCHWARM, MICHAEL
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Prepn. of racemic aminoalcohols of formula (I) by redn. of alpha -oximiocarboxylic acids or their esters of formula (II) is carried out using an alkali metal borohydride, in combination with hydrogen chloride or sulphuric acid as activator, in a solvent. R1 = linear, branched or cyclic alkyl, aralkyl or aryl gp. of u to 20C, opt. contg. heteroatoms such as O, N or S; R2 = H or 1-4C alkyl.