ANALGESIC DIBENZOXAZEPINES AND DIBENZOTHIAZEPINES

ANALGESIC DIBENZOXAZEPINES AND DIBENZOTHIAZEPINES

The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: Formula I which are useful as analgesic agents for the treatment of pain, and for prostaglandin-E2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HANSEN, DONALD, WILLIS, JR, PETERSON, KAREN, BERENICE
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: Formula I which are useful as analgesic agents for the treatment of pain, and for prostaglandin-E2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal, and a method for treating prostaglandin-E2 mediated diseases in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.