ASSAY DEVICES USING SUBSURFACE FLOW

ASSAY DEVICES USING SUBSURFACE FLOW

The present invention is directed to improving the performance of assays using a disposable assay device which includes a porous material in liquid communication with a capillary track. In particular, the capillary track is used in conjunction with the solid support to direct test sample and assay r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SIEGEL, NEAL, A, MORICI, LAURA, S, MUETTERTIES, ANDREW, J, ROPELLA, PAUL, J, FORNEY, KEVIN, J, GEIST, JILL, M, LOOMIS, NEIL, W, SCHAPIRA, THOMAS, G, PARSONS, ROBERT, G, PUTMAN, JILL, M, WAGNER, BRIAN, K, BASORE, BOB, O
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
TESTING
TRANSPORTING
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Beschreibung
Zusammenfassung:The present invention is directed to improving the performance of assays using a disposable assay device which includes a porous material in liquid communication with a capillary track. In particular, the capillary track is used in conjunction with the solid support to direct test sample and assay reagents directly to a defined reaction site on or in the porous material. Signal development at the reaction site indicates the assay result. The present invention is also directed to the construction of a disposable assay device which includes a capillary track. In particular, the cappillary track is formed by printing a fluid insoluble material, in the reverse image of the desired capillary track, on a film layer and then capping the printed material. Alternatively, the capillary track is formed by printing a fluid insoluble material, in the reverse image of the desired capillary track, on a porous material which is then sandwiched between two film layers.