Substituted m-xylylene diamines for the treatment of diseases of the central nervous system

Pharmaceutical compounds of the formula: in which A is B is R to R are each hydrogen or C1-4 alkyl, m, n and p are each 0, 1, or 2, q is 0, 1, 2 or 3, X and Z are each C1-4 alkyl, C1-4 alkoxy, hydroxy, nitro, cyano, halo, trihalomethyl, carboxy, C1-4 alkoxy-carbonyl or phenyl, and in addition Z, tog...

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Hauptverfasser: TIMMS, GRAHAM HENRY, CLARK, BARRY PETER
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Pharmaceutical compounds of the formula: in which A is B is R to R are each hydrogen or C1-4 alkyl, m, n and p are each 0, 1, or 2, q is 0, 1, 2 or 3, X and Z are each C1-4 alkyl, C1-4 alkoxy, hydroxy, nitro, cyano, halo, trihalomethyl, carboxy, C1-4 alkoxy-carbonyl or phenyl, and in addition Z, together with the phenyl ring to which it is attached, can be: Y is -O-, -S- or -CH2-, V is -(CH2)r- or -(CH2)rS- where r is 1 to 15, and W is hydrogen or optionally substituted phenyl; and salts thereof.