Vasoactive intestinal peptide analogs for treating smooth muscle disorders and/or asthma

A polypeptide represented by formula (I): wherein R represents Asp or Gly; R represents Asn or Gln; R represents Arg or Lys; R represents Val, Ala or Lys; R represents Lys or Leu; R represents Asn, Gln or Lys; R represents Ser, Lys or Ala; R represents Ile, Ala or Leu; R represents Leu or Lys; R rep...

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Bibliographische Detailangaben
Hauptverfasser:	NAKOSHI MASANAO C O SANWA KAGA, MITANI TAKAHIKO C O SANWA KAGA, TAKAHASHI HARUO C O SANWA KAGA, SAWAI KIICHI C O SANWA KAGAKU, HIRADE KINYA C O SANWA KAGAKU, KOBAYASHI YOHEI C O SANWA KAGA
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A polypeptide represented by formula (I): wherein R represents Asp or Gly; R represents Asn or Gln; R represents Arg or Lys; R represents Val, Ala or Lys; R represents Lys or Leu; R represents Asn, Gln or Lys; R represents Ser, Lys or Ala; R represents Ile, Ala or Leu; R represents Leu or Lys; R represents Asn, Lys or Arg; and X represents homoserine or homoserine lactone, which exhibits higher biological activities and higher stability than conventional VIP analogues.