Iodinated aroyloxy esters and their use as contrast agents in X-ray imaging

Iodinated aroyloxy esters and their use as contrast agents in X-ray imaging

Compounds having the structure wherein (Z &rparstr& COO is the residue of an iodinated aromatic acid; n is an integer from 1 to 20; R and R are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R and R are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl...

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Bibliographische Detailangaben
Hauptverfasser: BACON, EDWARD R, SPARA, PAUL P, DAUM, SOL J
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Compounds having the structure wherein (Z &rparstr& COO is the residue of an iodinated aromatic acid; n is an integer from 1 to 20; R and R are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R and R are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy, acylamino, acetamidoalkyl, COO-alkyl and cyano; R is alkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, alkoxyalkyl or acetamidoalkyl; are useful as contrast agents in x-ray imaging compositions and methods for x-ray diagnostic imaging.