Carbazolone derivatives and process for preparing the same

Carbazolone derivatives and process for preparing the same

The invention relates to carbazolone derivatives of the formula wherein A stands for a group of formula -CH2-R (V), wherein R means a hydroxyl or 2-methyl-1H-imidazol-1-yl group; B represents a group of formula wherein R1 means hydrogen or a methyl or ethyl group; or A and B together form a group of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CSEHI, ATTILA, BOD, PETER, HARSANYI, KALMAN, HORVATH NEE SZIKI, ERIKA, FEKECS, EVA, SZABO NEE KOML SI, GYOERGYI, MERSICH NEE DONAT, EVA, TRISCHLER, FERENC, HEGEDUS, BELA
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to carbazolone derivatives of the formula wherein A stands for a group of formula -CH2-R (V), wherein R means a hydroxyl or 2-methyl-1H-imidazol-1-yl group; B represents a group of formula wherein R1 means hydrogen or a methyl or ethyl group; or A and B together form a group of formula wherein R2 means a methyl or ethyl group; or A and B together form a group of formula The above compounds are useful intermediates in the synthesis of ondansetron of formula chemically 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-c arbazol-4-one. The invention further relates to a novel process for the preparation of compounds of the formula (I), wherein A and B are the same as in formula (I).