3-(Hydroxybenzylidenyl)-indoline-2-ones and pharmaceutical compositions containing them

The invention relates to compounds of the formula (I): in which R1, R2, R3, R4, R5 and X are as defined in the description, to their Z and E isomers, to their optical isomers, in the pure form or in a mixed form, and to their addition salts with a pharmaceutically acceptable acid or base. Medicament...

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Bibliographische Detailangaben
Hauptverfasser:	RENARD, PIERRE, LE BAUT, GUILLAUME, RENAUD DE LA FAVERIE, JEAN-FRANCOIS, NOURISSON, MARIE RENEE, CAIGNARD, DANIEL-HENRI, ADAM, GERARD, BIZOT-ESPIARD, JEAN-GUY
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to compounds of the formula (I): in which R1, R2, R3, R4, R5 and X are as defined in the description, to their Z and E isomers, to their optical isomers, in the pure form or in a mixed form, and to their addition salts with a pharmaceutically acceptable acid or base. Medicaments. L'invention concerne les composés de formule (I) : dans laquelle R1, R2, R3, R4, R5 et X sont tels que définis dans la description, leurs isomères Z et E, leurs isomères optiques, sous forme pure ou sous forme de mélange, et leurs sels d'addition à un acide ou une base pharmaceutiqement acceptable. Médicaments.