Protein C derivative

Human protein C derivatives with high activity and reduced dependence on thrombin activation are described. These derivatives differ from the native forms of human protein C in their increased activation rates, functional activities and carbohydrate structures. DNA compounds, transfer vectors, expre...

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Bibliographische Detailangaben
Hauptverfasser: GRINNELL, BRIAN WILLIAM, GERLITZ, BRUCE EDWARD
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Human protein C derivatives with high activity and reduced dependence on thrombin activation are described. These derivatives differ from the native forms of human protein C in their increased activation rates, functional activities and carbohydrate structures. DNA compounds, transfer vectors, expression vectors and transformants useful in producing these derivatives are also described.