DIAGNOSTIC TEST

PCT No. PCT/GB91/02228 Sec. 371 Date Aug. 30, 1993 Sec. 102(e) Date Aug. 30, 1993 PCT Filed Dec. 13, 1991 PCT Pub. No. WO92/10759 PCT Pub. Date Jun. 25, 1992.A diagnostic test can determine the occurrence of myocardial infarction or the total plasma antioxidant status as a marker of predisposition t...

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Hauptverfasser: RICE-EVANS, CATHERINE, ANNE, DAVIES, MICHAEL JONATHAN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:PCT No. PCT/GB91/02228 Sec. 371 Date Aug. 30, 1993 Sec. 102(e) Date Aug. 30, 1993 PCT Filed Dec. 13, 1991 PCT Pub. No. WO92/10759 PCT Pub. Date Jun. 25, 1992.A diagnostic test can determine the occurrence of myocardial infarction or the total plasma antioxidant status as a marker of predisposition to such an event, or the antioxidant status of other clinical and non-clinical samples. The test involves contacting a clinical sample in the presence of myoglobin and an oxidant therefor with a compound which reacts in that environment to form a chromogenic species with a characteristic absorption band in the visible spectrum spaced from potentially interfering bands attributable to haem proteins and other blood components.