Method for producing dichloromethylpyridines

A method for producing a dichloromethylpyridine of the formula (II): wherein each of R , R , R and R which are independent of one another, is a hydrogen atom, a halogen atom, an alkoxy group or a phenoxy group which may be substituted, provided that R , R , R and R are not simultaneously hydrogen at...

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Hauptverfasser: NASU, RIKUO, SHIMURA, TAKU, KATSUYAMA, ISAMU
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A method for producing a dichloromethylpyridine of the formula (II): wherein each of R , R , R and R which are independent of one another, is a hydrogen atom, a halogen atom, an alkoxy group or a phenoxy group which may be substituted, provided that R , R , R and R are not simultaneously hydrogen atoms, which comprises reacting a trichloromethylpyridine of the formula (I): wherein R , R , R and R are as defined above, with a reducing agent, wherein: (1) a dialkyl phosphite or a trialkyl phosphite is used as the reducing agent, and the reaction is conducted in the presence of a basic substance and an alcohol solvent, or (2) a trialkyl phosphine or triphenyl phosphine is used as the reducing agent, and the reaction is conducted in the presence of an alcohol solvent. o