TETRAHYDROPROTOBERBERINE QUATERNARY AMMONIUM COMPOUNDS AND THE PROCESS FOR PREPARING THEREOF
A tetrahydroprotoberberine quaternary ammonium compound represented by the general formula: R,R',X are as defined in the specification. Protoberberine is reduced by potassium borohydride to tetrahydroprotoberberine(I). Tetrahydroprotoberberine quaternary ammonium compounds are prepared by react...
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creator | ZHANG, CAN PENG, SIXUN WANG, YOUQUN YU, FENG HUANG, ZHENYA HUANG, WENGLONG DAI, DEZAI |
description | A tetrahydroprotoberberine quaternary ammonium compound represented by the general formula: R,R',X are as defined in the specification. Protoberberine is reduced by potassium borohydride to tetrahydroprotoberberine(I). Tetrahydroprotoberberine quaternary ammonium compounds are prepared by reaction of tetrahydroprotoberberine with halohydrocarbon in acetone or ethanol. These compounds can suppress arrhythmia and ventricular fibrillation, protect myocardial ischemia, and can be conveniently orally administered. |
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Protoberberine is reduced by potassium borohydride to tetrahydroprotoberberine(I). Tetrahydroprotoberberine quaternary ammonium compounds are prepared by reaction of tetrahydroprotoberberine with halohydrocarbon in acetone or ethanol. These compounds can suppress arrhythmia and ventricular fibrillation, protect myocardial ischemia, and can be conveniently orally administered.</description><edition>5</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1993</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19930526&DB=EPODOC&CC=EP&NR=0538844A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19930526&DB=EPODOC&CC=EP&NR=0538844A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHANG, CAN</creatorcontrib><creatorcontrib>PENG, SIXUN</creatorcontrib><creatorcontrib>WANG, YOUQUN</creatorcontrib><creatorcontrib>YU, FENG</creatorcontrib><creatorcontrib>HUANG, ZHENYA</creatorcontrib><creatorcontrib>HUANG, WENGLONG</creatorcontrib><creatorcontrib>DAI, DEZAI</creatorcontrib><title>TETRAHYDROPROTOBERBERINE QUATERNARY AMMONIUM COMPOUNDS AND THE PROCESS FOR PREPARING THEREOF</title><description>A tetrahydroprotoberberine quaternary ammonium compound represented by the general formula: R,R',X are as defined in the specification. Protoberberine is reduced by potassium borohydride to tetrahydroprotoberberine(I). Tetrahydroprotoberberine quaternary ammonium compounds are prepared by reaction of tetrahydroprotoberberine with halohydrocarbon in acetone or ethanol. 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Protoberberine is reduced by potassium borohydride to tetrahydroprotoberberine(I). Tetrahydroprotoberberine quaternary ammonium compounds are prepared by reaction of tetrahydroprotoberberine with halohydrocarbon in acetone or ethanol. These compounds can suppress arrhythmia and ventricular fibrillation, protect myocardial ischemia, and can be conveniently orally administered.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | TETRAHYDROPROTOBERBERINE QUATERNARY AMMONIUM COMPOUNDS AND THE PROCESS FOR PREPARING THEREOF |
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