NOVEL CYCLIC AMINOPHENYLACETIC ACID DERIVATIVE, PRODUCTION THEREOF, AND IMMUNE RESPONSE MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT

A novel cyclic aminophenylacetic acid derivative which has an immune response modulatory activity, represented by general formula (1), an optical isomer thereof and salts thereof, a process for producing the same, and a remedy for autoimmune diseases containing the same as an active ingredient. In Formula (1), R and R represent each independently hydrogen or C to C lower alkyl; R represents trifluoromethyl or phenyl which may be substituted by one to three groups selected among halogen, methoxy and combinations thereof; and X represents hydrogen, C to C lower alkyl, C to C lower alkoxy, cyano, thiocyano, trimethylsilylethynyl, phenyl which may be substituted by one to three groups selected among halogen, methoxy, methyl and combinations thereof, carbamoyl, carboxyl, C to C lower alkoxycarbonyl, acetyl, benzoyl, nitro, amino, C to C lower alkanoylamino, benzoylamino which may be substituted, phenylsulfonylamino which may be substituted, C to C lower alkylthio, C to C lower alkylsulfinyl, C to C lower alkylsulfonyl or halogen.