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An aqueous formulation for a conjugate of a mammalian superoxide dismutase with a polyethylene glycol (PEG-SOD), comprising PEG-SOD and a non-chelating buffer in the range from pH 5.0 to pH 6.5. Also disclosed is a method for using the formulation for the prevention and treatment of oxidant injury i...

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Bibliographische Detailangaben
Hauptverfasser:	RAJAGOPALAN NATARAJAN, REVELLO, KIM MARIE, NA, GEORGE C, YUAN, BARBARA OING
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	An aqueous formulation for a conjugate of a mammalian superoxide dismutase with a polyethylene glycol (PEG-SOD), comprising PEG-SOD and a non-chelating buffer in the range from pH 5.0 to pH 6.5. Also disclosed is a method for using the formulation for the prevention and treatment of oxidant injury in a mammal.