Compounds, vectors and methods for expressing human, cytosolic phospholipase A2

The invention includes recombinant DNA compounds, vectors and methods useful for expressing an exceptionally rare, human, cytosolic phospholipase A2 (cPLA2) enzyme. The invention also includes a method for screening compounds to identify inhibitors of cPLA2 which is believed to partake in several di...

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Hauptverfasser: SHARP, JOHN DAVID, KRAMER, RUTH MARIA, CHIOU, XUEIOU CHEN, HOSKINS, JO ANN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention includes recombinant DNA compounds, vectors and methods useful for expressing an exceptionally rare, human, cytosolic phospholipase A2 (cPLA2) enzyme. The invention also includes a method for screening compounds to identify inhibitors of cPLA2 which is believed to partake in several disease processes.