Inhibitors of HIV-1 reverse transcriptase

Novel aniline derivatives containing hydroxy and hydroxymethyl groups inhibit HIV-1 reverse transcriptase, and are useful in the prevention or treatment of infection by HIV-1 and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, wh...

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Bibliographische Detailangaben
Hauptverfasser:	HOLLOWAY, MARY KATHARINE, WAI, JOHN SUI MAN, SAARI, WALFRED S
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Novel aniline derivatives containing hydroxy and hydroxymethyl groups inhibit HIV-1 reverse transcriptase, and are useful in the prevention or treatment of infection by HIV-1 and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV-1 are also described.