Quinoline derivatives

Quinoline derivatives of the formula, wherein >A @ represents a group >N-(CH2)n-, >C=, >C=CH(CH2)n-, or >CH(CH2)n-, wherein n is an integer of 0-7; Y represents a group >C=O or >CHOH, R is a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, or an alkylthio group, R...

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Bibliographische Detailangaben
Hauptverfasser: SEKINE, KUMIKO, HASEGAWA, HIROSHI, TAIDO, NAOKATA, KOTSUGAI, TAKESHI, SHIOIRI, NORIAKI, SATO, SUSUMU, KURAISHI, TADAYUKI, ISOMAE, KAZUO
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Quinoline derivatives of the formula, wherein >A @ represents a group >N-(CH2)n-, >C=, >C=CH(CH2)n-, or >CH(CH2)n-, wherein n is an integer of 0-7; Y represents a group >C=O or >CHOH, R is a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, or an alkylthio group, R is a hydrogen atom, a halogen atom, an alkyl group, a hydroxy group, an alkoxy group, a phenyl group which may have a substituent, a phenoxy group, an alkanoyloxy group, or an amino group which may have a substituent, R is a hydrogen atom, a halogen atom, an alkyl group, or an alkoxy group, and m is an integer of 1-3. The compounds and their salts exhibit a superior anti-acetylcholinesterase activity with no side effects and are effective for the prevention or cure of senile dementia or memory disturbance.