Diazabicyclononyl derivatives as 5-HT3 receptor antagonists

Diazabicyclononyl derivatives as 5-HT3 receptor antagonists

Azabicyclo derivatives of formula (I) and pharmaceutically acceptable salts thereof: wherein A is a group of formula (a), (b) or (c): wherein R1 is hydrogen, C1-C10 alkyl, aralkyl or di(C1-C4) alkylamino(C1-C6)alkyl; R2, R3 and R4 may be the same or different and each is hydrogen, amino, halogen, C1...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HAYAKAWA, TORU, YAHATA, NOBUHIRO, KIKUCHI, HARUHIKO, MINO, SETSUKO, HAGIHARA, KOICHIRO, SATOH, HIROAKI, YANAI, MAKOTO
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Azabicyclo derivatives of formula (I) and pharmaceutically acceptable salts thereof: wherein A is a group of formula (a), (b) or (c): wherein R1 is hydrogen, C1-C10 alkyl, aralkyl or di(C1-C4) alkylamino(C1-C6)alkyl; R2, R3 and R4 may be the same or different and each is hydrogen, amino, halogen, C1-C4 alkoxy or phthalimide; X is O or NH; R is C1-C4 alkyl; and Y is NR, O or S; having 5-HT3 receptor antagonist activity.