Synthetic prosthetogens and their use in enzyme linked assays

An enzyme linked immunoassay procedure in which a primary enzyme whose concentration is related to the presence of analyte to be detected catalyses a primary enzymic reaction leading to a detectable product; wherein a substrate for the primary enzyme is a synthetic compound which is cleaved by the p...

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Bibliographische Detailangaben
Hauptverfasser:	TAYLORSON, CHRISTOPHER JOHN, RABIN, ROBERT, HOLLAWAY,MICHAEL ROBERT
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES DERIVATIVES THEREOF ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS SUGARS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	An enzyme linked immunoassay procedure in which a primary enzyme whose concentration is related to the presence of analyte to be detected catalyses a primary enzymic reaction leading to a detectable product; wherein a substrate for the primary enzyme is a synthetic compound which is cleaved by the primary enzyme to product directly, or by one or more further reactions, a component essential for the catalytic activity of another enzyme, which is thereby activated to catalyse a secondary enzymic reaction leading to a detectable result. A synthetic prosthetogen compound which is cleavable by an enzyme to produce a component essential for the catalytic activity of another enzyme, or a precursor therefor.