Method of diagnosing cancer

A method of diagnosing cancer with antibodies directed to non-cellular components in non-vascular, cellular secretions is disclosed. One such antibody is the monoclonal antibody Lu4B5, which was produced by immunizing mice with a purified, mucin containing fraction prepared from pooled bronchial was...

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Bibliographische Detailangaben
Hauptverfasser:	DEUTSCH, MARGARET A, PENCE, JEFFREY C, BAST, ROBERT C., JR, IGLEHART, J. DIRK
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method of diagnosing cancer with antibodies directed to non-cellular components in non-vascular, cellular secretions is disclosed. One such antibody is the monoclonal antibody Lu4B5, which was produced by immunizing mice with a purified, mucin containing fraction prepared from pooled bronchial washings from adenocarcinoma and large cell lung cancer patients. Lu4B5 monoclonal antibody reacts with the bronchial secretions of patients with primary bronchogenic carcinoma significantly more frequently than with secretions from patients without primary lung cancer.