NOVEL LYMPHOKINE/CYTOKINE GENES

Discoveries are disclosed that show particular aspects of recombinant DNA technology can be used successfully to produce hitherto unknown human lymphokine/cytokine-like proteins free of other lymphokines or cytokines. These proteins can be produced from DNA segments in cells or cell-free systems in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	ZIPFEL, PETER, F, LEONARD, WARREN, J, NAPOLITANO, MONICA, KELLEY, KATHLEEN, R, IRVING, STEVEN, G, SIEBENLIST, ULRICH
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Discoveries are disclosed that show particular aspects of recombinant DNA technology can be used successfully to produce hitherto unknown human lymphokine/cytokine-like proteins free of other lymphokines or cytokines. These proteins can be produced from DNA segments in cells or cell-free systems in various functional forms. These forms variously enable biochemical and functional studies of these novel proteins as well as production of antibodies. Means are described for determining the level of activation of genes for the lymphokine/cytokine-like proteins, for example, by measuring mRNA during mitogenic activation of isolated T cells or by measuring antigen secreted in extracellular or body fluids.