SPIROISOINDOLE COMPOUNDS

The present invention relates to spiroisoindolines of formula I that are antagonists at the phencyclidine receptor of the N-methyl-D-aspartate receptor complex and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides proc...

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Bibliographische Detailangaben
1. Verfasser: BARE, THOMAS MICHAEL
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to spiroisoindolines of formula I that are antagonists at the phencyclidine receptor of the N-methyl-D-aspartate receptor complex and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides processes for preparing the spiroisoindolines, intermediates useful for their synthesis, pharmaceutical compositions containing them, and methods for their use.