A METHOD OF PREPARING A FIBRINOGEN CONCENTRATE FROM BLOOD PLASMA, A DEVICE FOR CARRYING OUT SAID METHOD, AND A METHOD OF PREPARING FIBRINOGEN FROM SAID CONCENTRATE

A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 DEG C to a first temperature between -10 DEG C and -40 DEG C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separa...

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Hauptverfasser: WIJNGAARDS, GERRIT, VAN DOMMELEN, FREDERIK SUSAN
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VAN DOMMELEN, FREDERIK SUSAN
description A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 DEG C to a first temperature between -10 DEG C and -40 DEG C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separating the solid matter and the liquid main fraction of the plasma, viz. water, whereby the thawing is effected in steps from the first temperature to a conditioning temperature between -5 DEG C and -1 DEG C, after which the size of the solid material is reduced and the reduced material is brought to a temperature at which the main fraction of the plasma, viz. water, becomes liquid and the solubility of fibrinogen in said fluid is as low as possible, after which fluid is separated from the fibrinogen concentrate. The invention also relates to a device for carrying out this method.
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subjects CHEMISTRY
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
FOODS OR FOODSTUFFS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROTEIN COMPOSITIONS FOR FOODSTUFFS
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
WORKING-UP PROTEINS FOR FOODSTUFFS
title A METHOD OF PREPARING A FIBRINOGEN CONCENTRATE FROM BLOOD PLASMA, A DEVICE FOR CARRYING OUT SAID METHOD, AND A METHOD OF PREPARING FIBRINOGEN FROM SAID CONCENTRATE
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