A METHOD OF PREPARING A FIBRINOGEN CONCENTRATE FROM BLOOD PLASMA, A DEVICE FOR CARRYING OUT SAID METHOD, AND A METHOD OF PREPARING FIBRINOGEN FROM SAID CONCENTRATE

A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 DEG C to a first temperature between -10 DEG C and -40 DEG C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separa...

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Bibliographische Detailangaben
Hauptverfasser:	WIJNGAARDS, GERRIT, VAN DOMMELEN, FREDERIK SUSAN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY FOODS OR FOODSTUFFS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROTEIN COMPOSITIONS FOR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES WORKING-UP PROTEINS FOR FOODSTUFFS
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Beschreibung
Zusammenfassung:	A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 DEG C to a first temperature between -10 DEG C and -40 DEG C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separating the solid matter and the liquid main fraction of the plasma, viz. water, whereby the thawing is effected in steps from the first temperature to a conditioning temperature between -5 DEG C and -1 DEG C, after which the size of the solid material is reduced and the reduced material is brought to a temperature at which the main fraction of the plasma, viz. water, becomes liquid and the solubility of fibrinogen in said fluid is as low as possible, after which fluid is separated from the fibrinogen concentrate. The invention also relates to a device for carrying out this method.