Clear, stable cromolyn formulation

A substantially clear, sterile, aqueous tonicity adjusted composition of 1,3-bis(2-carboxychromon-5-yloxy)propan-2-ol, other bis-cromolyn derivatives, or pharmaceutically acceptable salts thereof, is provided which contains over 20 ppm transition metal ions or ions of Group IIA, IB, IIB or IV B. The...

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Bibliographische Detailangaben
Hauptverfasser: ZELEZNICK, LOWELL, RAFF, ALLAN M
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A substantially clear, sterile, aqueous tonicity adjusted composition of 1,3-bis(2-carboxychromon-5-yloxy)propan-2-ol, other bis-cromolyn derivatives, or pharmaceutically acceptable salts thereof, is provided which contains over 20 ppm transition metal ions or ions of Group IIA, IB, IIB or IV B. The composition is useful as an anti-inflammatory agent in the treatment of bronchial asthmatics and allergic or immune reactions in the eye and nose.