Azole derivatives and antiulcerative composition containing same

Compounds of the general formula (I): and pharmaceutically acceptable salts thereof, in which A, B, C and D each represent -CH= or -N=, with the proviso that at least one of them is -N=; X represents -NH-, -O- or -S-; Y represents -(CH2)p- wherein p is an integer from 0 to 4, -C(CH3)2-, -CH2CH=CH-,...

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Hauptverfasser: YUDA, YASUKATSU, MEIJI SEIKA K. K. YAKUHIN SOGO, INOUYE, SHIGEHARU, MEIJI SEIKA K. K. YAKUHIN SOGO, YAMAZAKI, NAOKI, MEIJI SEIKA K. K. YAKUHIN SOGO, SHIBAHARA, SEIJI, MEIJI SEIKA K. K. YAKUHIN SOGO, TSURUOKA, TAKASHI, MEIJI SEIKA K. K. YAKUHIN SOGO, NISHIO, MOTOHIRO, MEIJI SEIKA K. K. YAKUHIN SOGO, TOMOMOTO, TAMAKO, MEIJI SEIKA K. K. YAKUHIN SOGO, HIRANO, FUMIYA, MEIJI SEIKA K. K. YAKUHIN SOGO, KONNO, FUKIO, MEIJI SEIKA K. K. YAKUHIN SOGO, KATANO, KIYOAKI, MEIJI SEIKA K. K. YAKUHIN SOGO, OGINO, HIROKO, MEIJI SEIKA K. K. YAKUHIN SOGO, MACHINAMI, TOMOYA, MEIJI SEIKA K. K. YAKUHIN SOGO
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Compounds of the general formula (I): and pharmaceutically acceptable salts thereof, in which A, B, C and D each represent -CH= or -N=, with the proviso that at least one of them is -N=; X represents -NH-, -O- or -S-; Y represents -(CH2)p- wherein p is an integer from 0 to 4, -C(CH3)2-, -CH2CH=CH-, -CH2CO-, -CF2- or -CH2COCH2-; R represents a hydrogen atom, a C1-4 alkyl group, a halogen atom or a C1-4 alkoxy group; R represents a hydrogen atom, a hydroxyl group, a saturated or unsaturated C1-6 alkyl group, a C1-6 alkoxy group, a carboxyl group, a saturated or unsaturated C1-12 alkoxycarbonyl group which may be optionally substituted, a cycloalkoxycarbonyl group, a saturated or unsaturated five- or six-membered heterocyclic group containing at least one nitrogen atom optionally with one or more nitrogen and/or oxygen atoms, which may be optionally condensed and/or substituted, -CONR R , -NR R , -OCOR or -NHCONHR wherein R and R , which may be the same or different, represent a C1-6 alkyl group which may be optionally substituted or a cycloalkyl group, and m and n each represent an integer from 0 to 2.