MEDICAL MATERIAL PERMITTING CELLS TO ENTER THEREINTO AND ARTIFICIAL SKIN

An improved medical material, penetrable by cells, which contains modified collagen being 0-80% of helical structure and a carrier (1) which has a higher resistance to enzymatic decomposition than the collagen. The modified collagen is a collagen from which the terminal part having an antigen is rem...

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Hauptverfasser: OHSAKI, KENICHI TERUMO KABUSHIKI KAISHA 2656-1, KATAKURA, TAKEO TERUMO KABUSHIKI KAISHA 2656-1, MORI, YUICHI, TATEBE, KEN TERUMO KABUSHIKI KAISHA 2656-1, KONISHI, JUN TERUMO KABUSHIKI KAISHA 2656-1, KOIDE, MIKIO TERUMO KABUSHIKI KAISHA 2656-1, OYAMADA, KAORU TERUMO KABUSHIKI KAISHA 2656-1, YOSHISATO, KATSUTOSHI
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An improved medical material, penetrable by cells, which contains modified collagen being 0-80% of helical structure and a carrier (1) which has a higher resistance to enzymatic decomposition than the collagen. The modified collagen is a collagen from which the terminal part having an antigen is removed. The carrier (1) can be collagen, fibroin polylactic acid, muco polyglucose or alginic acid. It can also be a modified collagen from which the terminal part having an antigen is removed, or a collagen, having an introduced cross-linked structure or a fibrilised collagen with or without an introduced cross-linked structure. The medical material has the structure of a film, or a sponge with the carrier contained in the matrix. An artificial skin comprises, as a wound-contacting layer, this medical material in which fibrilised collagen in dispersed in the modified collagen which is in matrix condition, a supporting layer made of fibroin, and a water transmitting layer laminated on the other side of the supporting layer. An anti-bacterial agent is contained in at least one of the layers.