Gel filtration of heat treated factor VIII

Gel filtration of heat treated factor VIII

Highly purified antihemophilic factor is produced by a process comprising a PEG precipitation step, a gel filtration step and a heat treating virus inactivation step. Al(OH)3 adsorption and PEG precipitation carried out at room temperature allow processing to proceed directly to a gel filtration ste...

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Bibliographische Detailangaben
Hauptverfasser: BOCKSKOPF, BERND, SENG, RICHARD L, BROCKWAY, WILLIAM, GOELKER, CHRISTIAN
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Highly purified antihemophilic factor is produced by a process comprising a PEG precipitation step, a gel filtration step and a heat treating virus inactivation step. Al(OH)3 adsorption and PEG precipitation carried out at room temperature allow processing to proceed directly to a gel filtration step.