Method and composition for the treatment and prevention of viral infections

The invention provides a method of treating a viral infection in a subject, which comprises administering a protease enzyme, especially a plant protease such as, for example a bromelain, papain or ficin. Examples of viral infections which may be treated include infections with DNA- or RNA-containing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	OXFORD, JOHN SYDNEY, SUTTON, PETER MORGAN
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The invention provides a method of treating a viral infection in a subject, which comprises administering a protease enzyme, especially a plant protease such as, for example a bromelain, papain or ficin. Examples of viral infections which may be treated include infections with DNA- or RNA-containing viruses or infections caused by prions. The invention further provides the use of proteases in the production or sterilization of pharmaceutical preparations or food-stuffs in order to reduce the content of virus, pro-virus or virus-infected cells therein and the use of proteases in the sterilization or decontamination of surgical devices. Production of inactivated or attenuated virus for incorporation into a vaccine or vaccine component for providing a protective effect against viral infection in humans or animals is also described.