Compounds for the introduction of a mercapto group to tyrosin
Compounds of the general formula in which A represents an amine-substituted aromatic radical and X represents a hydrocarbon radical having 1 to 10 carbon atoms, are prepared by reaction of a pyridyldithiocarbonic acid N-hydroxysuccinimide ester with the hydrazide of an aromatic carboxylic acid which...
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| Format: | Patent |
| Sprache: | eng ; fre ; ger |
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| Zusammenfassung: | Compounds of the general formula
in which A represents an amine-substituted aromatic radical and X represents a hydrocarbon radical having 1 to 10 carbon atoms, are prepared by reaction of a pyridyldithiocarbonic acid N-hydroxysuccinimide ester with the hydrazide of an aromatic carboxylic acid which is substituted by amine on the aromatic ring and are used for the introduction of an SH group into a tyrosine, in particular into a tyrosine or tyrosine derivative bonded in a peptide or protein. |
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