Antibacterial and antitumor agents LL-E33288 epsilon-I and LL-E33288-epsilonBr, with processes and intermediates for producing said agents

Antibacterial and antitumor agents designated LL-E33288 epsilon -I and LL-E33288 epsilon -Br, their production by strains of Micromonospora echinospora ssp. calichensis designated NRRL-15839, NRRL-15975 and NRRL-18149, and chemical processes for their production, are disclosed. Novel intermediates p...

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Bibliographische Detailangaben
Hauptverfasser: ELLESTAD, GEORGE A, MCGAHREN, WILLIAM JAMES
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Antibacterial and antitumor agents designated LL-E33288 epsilon -I and LL-E33288 epsilon -Br, their production by strains of Micromonospora echinospora ssp. calichensis designated NRRL-15839, NRRL-15975 and NRRL-18149, and chemical processes for their production, are disclosed. Novel intermediates prepared in the chemical processes are disclosed. Processes for producing reductively aromatized derivatives of other antibiotics are also disclosed.