Glass fibers coated with agarose for use as column packing or chromatographic media for bioseparations

The invention discloses a glass fiber coated with a porous hydrophilic matrix material comprised of agarose which is derivatized to bind a suitable ligand or biological material. The glass fibers of the present invention are useful in removing contaminates in a chromatographic process. In one embodi...

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Bibliographische Detailangaben
Hauptverfasser:	HENDERSON, MARY BETH, DOWNEY, WILLIAM EDWARD, NISHIOKA, GARY MASARU
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SEPARATION SPIRITS TESTING THEIR RELEVANT APPARATUS TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a glass fiber coated with a porous hydrophilic matrix material comprised of agarose which is derivatized to bind a suitable ligand or biological material. The glass fibers of the present invention are useful in removing contaminates in a chromatographic process. In one embodiment glass fibers have on their surface a coating comprising agarose and polymyxin B which coated glass fibers are useful for removing endotoxins in a bioseparation process.