HUMAN MONOCLONAL ANTIBODY AND DRUG FOR PROPHYLAXIS AND TREATMENT OF INFECTIOUS DISEASES COMPRISING SAME AS EFFECTIVE INGREDIENT

A human monoclonal antibody which reacts with several O antigens of Pseudomonas aeruginosa (esp. with O antigens of type A+F, D+I, E+F, or G+H) is obtd. by culture of a suitable antibody-producing cell line which may be either a virus-transformed cell line (e.g. Epstein-Barr virus-transformed) or a...

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Hauptverfasser: FUKUDA, TAMOTSU, ONO, YASUSHI, SHIGETA, SHIRO, KUROIWA, YASUYUKI, OOKA, HISAYOSHI
Format: Patent
Sprache:eng
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Zusammenfassung:A human monoclonal antibody which reacts with several O antigens of Pseudomonas aeruginosa (esp. with O antigens of type A+F, D+I, E+F, or G+H) is obtd. by culture of a suitable antibody-producing cell line which may be either a virus-transformed cell line (e.g. Epstein-Barr virus-transformed) or a hybridoma derived from human or animal cells, and esp. from normal lymph cells. The antibody is obtd. by culture of one of the following cell lines: MP-5082 (FERM P9745); MP-4095 (FERM-P 9750); MP-5064 (FERM-P 9751); MP-5075 (FERM-P 9752); MP-5104 (FERM-P 9753); MP -5038 (FERM-BP 1596); MP-5035 (FERM-BP 1598) or MP-5046 (FERM -BP 1599).