Novel immunosuppressant agent

Described is a process for producing a new immunosuppressant, "immunomycin", by novel fermentation conditions of Streptomyces hygroscopicus var. ascomyceticus. The immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e.g. bone marrow and heart transp...

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Bibliographische Detailangaben
Hauptverfasser:	SIGAL, NOLAN H, BORRIS, ROBERT P, BYRNE, KEVEN M, MONAGHAN, RICHARD L, KAPLAN, LOUIS, DUMONT, FRANCIS J, ZINK, DEBORAH L, GARRITY, GEORGE M
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Described is a process for producing a new immunosuppressant, "immunomycin", by novel fermentation conditions of Streptomyces hygroscopicus var. ascomyceticus. The immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e.g. bone marrow and heart transplants. Also described is a new method of use utilizing known "ascomycin" as an immunosuppressant.