METHOD FOR THE IDENTIFICATION OF ANTIGENS EXPRESSED IN VIVO, DIAGNOSTIC ASSAYS THEREFOR AND VACCINES CONTAINING THEM

A method for identifying all of the antigens from a pathogenic organism such as Epstein-Barr Virus which are expressed in vivo comprises generating a gene bank using nucleic acid fragments which include all of the nucleic acid from a given organism and direct screening of said gene bank with serum f...

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Hauptverfasser: WALLS, DERMOT FELIX GERARD, GANNON, BERNARD FRANCIS XAVIER
Format: Patent
Sprache:eng
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Zusammenfassung:A method for identifying all of the antigens from a pathogenic organism such as Epstein-Barr Virus which are expressed in vivo comprises generating a gene bank using nucleic acid fragments which include all of the nucleic acid from a given organism and direct screening of said gene bank with serum from a subject with clinical symptoms caused by the pathogenic organism. The antigens identified can be used as a basis for various diagnostic assays and for preparing vaccines.