POLYPEPTIDES WITH A PROUROKINASE ACTIVITY, THEIR PRODUCTION AND USE

The polypeptides differ from prourokinase by N-terminal truncations, or N-terminal truncations in conjunction with replacement of another amino acid. The polypeptides are prepared by genetic manipulation and have thrombolytic properties.

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Bibliographische Detailangaben
Hauptverfasser: KOERWER, WOLFGANG, BALDINGER, VERENA, DOERPER, THOMAS, KURFURST, MANFRED, SCHWARZ, MARGARETE
Format: Patent
Sprache:eng ; ger
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Zusammenfassung:The polypeptides differ from prourokinase by N-terminal truncations, or N-terminal truncations in conjunction with replacement of another amino acid. The polypeptides are prepared by genetic manipulation and have thrombolytic properties.