1,2,3,4-Tetrahydroisoquinoline antiarrhythmic agents

1,2,3,4-Tetrahydroisoquinoline antiarrhythmic agents

Isoquinoline antiarrhythmic agents of the formula:- and their pharmaceutically acceptable salts, wherein one of R and R is methoxy and the other is a group of the formula -OH, -O.CO(C1-C4 alkyl), -O.COPh or -O.COCH2Ph where Ph is a phenyl group optionally substituted by one or two substituents each...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: CUSSANS, NIGEL JOHN DR
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Isoquinoline antiarrhythmic agents of the formula:- and their pharmaceutically acceptable salts, wherein one of R and R is methoxy and the other is a group of the formula -OH, -O.CO(C1-C4 alkyl), -O.COPh or -O.COCH2Ph where Ph is a phenyl group optionally substituted by one or two substituents each independently selected from F, Cl, Br, I, CF3, C1-C4 alkyl and C1-C4 alkoxy.