Nonglycosylated plasminogen activator and method of preparation

Novel, structurally modified plasminogen activators are provided which are incapable of receiving N-linked carbohydrate residues. The amino acid modified forms of the plasminogen activators retain their specific plasminogen activator activity and, thus, continue to function to activate plasminogen i...

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Hauptverfasser: MOIR, DONALD T, BALTIMORE, DAVID, BROEZE, ROBERT J
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creator MOIR, DONALD T
BALTIMORE, DAVID
BROEZE, ROBERT J
description Novel, structurally modified plasminogen activators are provided which are incapable of receiving N-linked carbohydrate residues. The amino acid modified forms of the plasminogen activators retain their specific plasminogen activator activity and, thus, continue to function to activate plasminogen in initiating blood clot lysis.
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language eng ; fre ; ger
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Nonglycosylated plasminogen activator and method of preparation
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