COLLAGENASE INHIBITOR DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

COLLAGENASE INHIBITOR DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The compounds correspond to the general formula …… in which… -W denotes a residue of an amino acid chosen from valine, lysine, norleucine and methionine, and… -Z denotes an amino or alkylamino radical in which the alkyl part, which contains 1 or 2 carbon atoms, is substituted by a phenyl or trifluor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FOURNIE-ZALUSKI, MARIE-CLAUDE, CARTWRIGHT, TERENCE, BOUBOUTOU-TELLO, ROMAINE, LELIEVRE, YVES
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The compounds correspond to the general formula …… in which… -W denotes a residue of an amino acid chosen from valine, lysine, norleucine and methionine, and… -Z denotes an amino or alkylamino radical in which the alkyl part, which contains 1 or 2 carbon atoms, is substituted by a phenyl or trifluorophenyl radical, and also include their diastereoisomers and their addition salts with pharmaceutically acceptable acids. … The invention finds application especially in the pharmaceutical industry.