Human protein S, A plasma protein regulator of hemostasis

The present invention comprises novel DNA compounds which encode human protein S activity. The human protein S cDNA sequence consists of a coding region for a 676 amino acid precursor; the coding region encodes a 41 amino acid leader peptide, 635 amino acids corresponding to the mature protein, and...

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Bibliographische Detailangaben
Hauptverfasser:	LONG, GEORGE LOUIS, HOSKINS, JO ANN
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention comprises novel DNA compounds which encode human protein S activity. The human protein S cDNA sequence consists of a coding region for a 676 amino acid precursor; the coding region encodes a 41 amino acid leader peptide, 635 amino acids corresponding to the mature protein, and a stop codon. Eukaryotic expression vectors have been constructed which comprise the novel protein S activity-encoding DNA and drive expression of protein S when transformed into an appropriate host cell.