Detection of inflammation and novel antibodies therefor

An assay, test kit and novel antibodies for use therein are provided for detecting the presence of inflammation caused, for instance, by infectious disease or immune dysfunction, measures the level of IL-1 in body fluid, such as serum. Various assay techniques may be employed including direct assays...

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Bibliographische Detailangaben
Hauptverfasser:	PRICKETT, KATHRYN SUSAN, CONLON, PAUL JEROME III
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	An assay, test kit and novel antibodies for use therein are provided for detecting the presence of inflammation caused, for instance, by infectious disease or immune dysfunction, measures the level of IL-1 in body fluid, such as serum. Various assay techniques may be employed including direct assays, competitive assays and double determinant assays. The assay and test kit employs novels polyclonal or monoclonal antibodies specific for unique antigenic sites on the IL-1 protein or IL-1 peptide.